EndometriosisAbout 10% of women of reproductive age suffer from endometriosis, 40-50% of patients with endometriosis have infertility. The genital is the most common (90-94%) form of endometriosis, the extra genital localization of endometriosis occurs in 6-8% of cases. The results of genetic studies indicate that the probability of the development of endometriosis is 3-10 times higher among relatives of the first degree of affinity comparing with women of control group. The highest frequency of endometriosis is met among women who undergo laparoscopic surgery with the purpose of identifying the causes of infertility and pelvic pain (endometriosis is diagnosed from 20% to 50% of cases). Read more

Standardization of medical care

  • The Order of the MoH of Ukraine of 06.04.2016 №319 “On approval and implementation of medical and technological documents on standardization of medical care in genital endometriosis”Read more

Public medical organizations

Clinical trials including adults /in adults, adults & children/

  • Globally, there are 30 recruiting clinical trials (all trials – 182) for endometriosis, including 3 Phase I and 5 Phase IV trials at ClinicalTrials.gov.
  • World leaders: the USA – 6, Egypt/France – 5, Belgium – 3 recruiting trials.
  • CEE leaders: Poland/the Russian Federation/Ukraine – 1 recruiting trial.
  • Ukraine: 1 recruiting Phase II clinical trial for endometriosis is conducted on 5 clinical sites: Ivano-Frankivsk – 1, Kyiv – 4 sites. The country experience includes 5 Phase II and III clinical trials totally on 10 clinical sites in 7 cities. The city leaders by the number of clinical trials: Kyiv – 5, Zaporizhia/Vinnytsia – 2 trials. The city leaders by the number of clinical sites: Kyiv – 4, Chernivtsi/Dnipro/Ivano-Frankivsk/Odesa/Vinnytsia/Zaporizhia – 1 site.

Clinical trials on medical devices

  • Globally, there are 5 recruiting clinical trials, including Phase I trial in Belgium.
  • World leaders: Egypt – 2, Belgium/Brazil/Spain – 1 recruiting trial.
  • CEE leaders: no recruiting clinical trials.

Clinical trials with stem cells

  • Globally, no recruiting clinical trials.

clinical trials for endometriosis incl adults in CEE

clinical trials for endometriosis incl adults in Ukraine

Clinical trials including children /pediatric, in children & adults/

  • Globally, no recruiting clinical trials; all clinical trials for endometriosis – 11 at ClinicalTrials.gov.
  • World leaders (all trials): the USA – 5, Belgium – 2, other countries – 1 trial.
  • CEE leaders (all trials): Austria/the Czech Republic – 1 trial.

Non-interventional studies including adults /in adults, adults & children/

  • Globally, there are 17 recruiting observational studies, including 1 study on medical devices in France at ClinicalTrials.gov.
  • World leaders: France – 3, Denmark/Italy/Turkey/the USA – 2 recruiting studies.
  • CEE leaders: no recruiting studies.

Non-interventional studies including children /pediatric, in children & adults/

  • Globally, 5 recruiting observational studies for endometriosis; studies on medical devices – 0 at ClinicalTrials.gov.
  • World leaders: Denmark/the Republic of Korea/Turkey/the United Kingdom/the USA – 1 recruiting study.
  • CEE leaders: no recruiting studies.

NB! The cities located on the non-controlled territories of Ukraine are not included in the statistics.

Publications of

Sergii Gromov

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