The problem of treatment of chronic pain is complex, and its high importance is shown particularly in the statistics of the National Cancer Registry of Ukraine, 2014: the Prevalence of cancer: 909.087 patients or rate – 2507.2 patients per 100 thousand population (males – 1903.3; females – 3030.2). The Incidence of malignant tumors: 135,307 new cases or rate (age-standardized, world standard) – 223.7 new cases per 100 thousand population (males – 267.1; females – 202.2). The Mortality of malignant tumors: 67,189 deaths or rate (age-standardized, world standard) – 105.6 deaths per 100 thousand population (males – 151.4; females – 77.0). The Incidence of malignant tumors (children): 1034 new cases or rate (age-standardized, world standard) – 15.6 new cases per 100 thousand children population (males – 17.0; females – 14.1). The Mortality of malignant tumors (children): 280 deaths or rate (age-standardized, world standard) – 3.9 deaths per 100 thousand children population (males – 4.4; females – 3.4).
Standardization of medical care
- The Order of the MoH of Ukraine of 25.04.2012 №311 “On approval and implementation of medical and technological documents on standardization of medical care in Chronic pain syndrome”.
Public medical organizations
- The Ukrainian Society of Anaesthesiologists
- Charitable organization “Association of palliative and hospice care”
- International Association for the support of conservative Oncology in Ukraine
Clinical trials including adults /in adults, adults & children/
- Globally, there are 325 recruiting clinical trials for chronic pain, including 23 Phase I and 30 Phase IV trials at ClinicalTrials.gov.
- World leaders: the USA – 152, Canada – 32, Spain – 20 recruiting trials.
- CEE leaders: Hungary/Poland – 4, Bulgaria/the Czech Republic – 2, other countries – 1 recruiting trial.
- Ukraine: 1 recruiting clinical trial is conducted on 20 clinical sites in 8 cities. The country experience includes 6 Phase II, III, and IV clinical trials for chronic pain totally conducted on 27 clinical sites in 13 cities. The city leaders by the number of clinical trials: Kyiv – 6, Kharkiv – 5, Lviv/Odesa – 4 trials. The city leaders by the number of clinical sites: Kyiv – 7, Vinnytsia – 4, Odesa – 3 sites.
Clinical trials on medical devices
- Globally, there are 85 recruiting clinical trials, including 3 Phase I trials.
- World leaders: the USA – 40, France – 9, Belgium – 7 recruiting trials.
- CEE leaders: no recruiting clinical trials.
Clinical trials with stem cells
- Globally, there are 2 recruiting clinical trials, including Phase I trial in the Republic of Korea.
- World leaders: Australia/the Republic of Korea/the USA – 1 recruiting trial.
- CEE leaders: no recruiting clinical trials.
Clinical trials including children /pediatric, in children & adults/
- Globally, there are 24 recruiting clinical trials for chronic pain; Phase I – 2, Phase IV – 0 trials.
- World leaders: the USA – 11, Belgium/France/Germany/the United Kingdom – 2, other countries – 1 recruiting trial.
- CEE leaders: Bulgaria/Croatia/Hungary/Slovakia/Slovenia – 1 clinical trial.
- Ukraine: no recruiting clinical trials. No country experience for chronic pain.
Clinical trials on medical devices
- Globally, there are 2 recruiting clinical trials, Phase I – 0 trials.
- World leaders: Canada/Denmark – 1 recruiting trial.
- CEE leaders: no recruiting clinical trial.
Clinical trials with stem cells
- Globally, no recruiting clinical trials.
Non-interventional studies including adults /in adults, adults & children/
- Globally, there are 77 recruiting observational studies for chronic pain, including 14 studies on medical devices.
- World leaders: the USA – 27, France – 11, the United Kingdom – 9 recruiting studies.
- CEE leaders: Austria – 2, Croatia – 1 recruiting study.
Non-interventional studies including children /pediatric, in children & adults/
- Globally, there are 19 recruiting observational studies for chronic pain, including 3 studies on medical devices.
- World leaders: France – 6, Sweden/the United Kingdom /the USA – 4, Germany/Italy – 3 recruiting studies.
- CEE leaders: Austria only – 1 recruiting study.
NB! The cities located in the non-controlled territories of Ukraine are not included in the statistics.
